What's In It For You With Liposomal Clodronate Therapy

By Teri Farley


Everyday scientists and medical doctors work together to discover possible treatments, more likely a better one, for various medical diseases. Up until now, several medical conditions remain incurable such as AIDS and Cancer. But with continuous medical study and experimentation, some experiments have shown promising results, for an instance in autoimmune diseases such as that with liposomal clodronate.

True enough, the results on the several studies for such therapy were very promising, offering a new hope for patient suffering from immune system abnormalities. Liposome clodronate differs from any kind of therapy as it is delivered intracellularly. With the use of several advancements in medical therapy, treatment of medical diseases have become quite sophisticated indeed.

The immune system has an important role in a man's health. Under normal circumstances, the immune system defends the body from foreign cells which may cause infection such as common cough and colds. In addition to that, it may also send off several defensive mechanisms in the body perhaps to prevent additional trauma.

Inflammatory marker as the name implies is a sign that inflammation is currently going on. Famous inflammatory markers includes interleukin 6,8 and 1 as well as TNF-alfa. However, these markers are only a tiny part of the immune system. Indeed, the immune system consists of thousands of cells all of which has its own tiny role.

Clodronic acid liposome therapy, targets the macrophages to efficiently halt the attack of healthy cells. Suppressing your macrophages will slow down inflammation thus decreasing the pace of disease progression. Some autoimmune diseases have life threatening effect when not intervened properly, for an instance in myasthenia gravis.

Autoimmune diseases are medical conditions caused by the immune system itself. Macrophages, the core cell of the immune system, attack healthy cells causing inflammation such as those in multiple sclerosis, pernicious anemia, rheumatoid arthritis and so on. During transplant, macrophages may also attack the new cells coming from the graft causing the body to reject it.

To be able to reduce or halt these immune reactions, it will be necessary to suppress the immune system. Although this mode of treatment is not new, not all method of therapy has proved to be quite a success. Transplant rejections are still prominent and disease progression on patients with autoimmune disease is still unpreventable.

With the discovery of these new therapy, it surely increases the hope of anyone suffering from severe autoimmune diseases to achieve disease remission. This may also decrease the chances of transplant rejection to those patients scheduled for transplantation in any parts of the body. All in all, clodronic acid liposome therapy is promising a good quality of life among patients.

Liposomal clodronate was also discovered to have therapeutic effects in conjunction with anti tumor drugs used in Cancer. Clodronic acid is said to improve the drug absorption of antineoplastic drugs as well as demonstrated the possibility of slowing down cancer growth however, this mode of action is yet to be proved. The combination of decreasing blood vessel density and tumor size shows great promise.




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